Pdf pet using 18ffdg for treatment monitoring in patients with lymphoma is one of the most. Analysis of the deauville criteria for the assessment of. Deauville categories translate to thresholds on the qpet scale. This algorithm has been developed for md anderson using a multidisciplinary approach considering circumstances particular to md andersons specific patient population, services and structure. All that glitters is not gold new reconstruction methods. The role of 18ffdg petct in multiple myeloma staging. Fdgpet scan in assessing lymphomas and the application of. Awan ue1, siddiqui n, saadullah m, bashir h, farooqui zs, muzaffar n, mahmmood mt. We investigated the value of posttreatment petct in predicting the prognosis of dlbcl patients when interpreted according to qualitative visual trichotomous assessment qvta criteria compared with the deauville criteria. Deauville criteria concern that mbp 2cm background download fulltext pdf download fulltext pdf. Hopkins criteria can be as an example for visual criteria used in nsclc 6. All that glitters is not gold new reconstruction methods using deauville criteria for patient. The deauville fivepoint scale deauville 5ps is an internationallyrecommended scale for routine clinical reporting and clinical trials using fdg petct in the initial staging and assessment of treatment response in hodgkin lymphoma hl and certain types of nonhodgkin lymphomas nhl. The use of deauville criteria in followup assessment of response to therapy in extranodal nonhodgkins lymphoma.
Hodgkin lymphoma page 1 of 1 md anderson cancer center. Two readers independently assessed response by ihp and deauville criteria. Petct was incorporated into the lymphoma response criteria in 2007. In a retrospective analysis of patient data we assessed the prognostic relevance of the deauville score fivepoint scale on petct and circulating epsteinbarr virus dna after completion of treatment in consecutive patients with enktl who met eligibility criteria newly diagnosed and received nonanthracyclinebased chemotherapy, concurrent chemoradiotherapy, or both together diagnosed at. Ffdg uptake of the tumour with that of the mediastinum and liver. Pdf the use of deauville criteria in followup assessment of.
A, b, and d had consensus responses for the 4 criteria eortc, percist, peter mac, and deauville. Ash 2016 5point deauville criteria assessed interim pet. Highdose salvage chemotherapy followed by haematopoietic stem cell transplantation hct is the standard of care in transplant eligible relapsedrefractory rr classical hodgki. This is interesting, since the visual evaluation methods is generally thought to be the most subjective method. In a radiationnaive patient, tli may be an appropriate component of hdt.
All subjects unde images were evaluated with the ihp criteria, deauville score of 3 dc4. The trend toward simplification of response assessment may lead in the future to a single set of response criteria for both hematologic and solid organ malignancies that could be used in place of the currently disparate lymphoma response criteria and response evaluation criteria in solid tumors recist systems. Haplohsct is a therapeutic option for patients with highrisk hematologic neoplasms with the advantages of quick availability, easy programation and logistics, and a committed donor. Interreader reliability of early fdgpetct response. Imaging for staging and response assessment in lymphoma. In this retrospective cohort study, we investigated the prognostic significance of fdgpet interpreted by both standard and deauville criteria among 42 consecutive patients with relapsedrefractory rr hl undergoing allohct from 20042012. Criteria in solid tumors percist criteria are the more frequently used semiquantative criteria in pet evaluation.
The european experts with a published or personal experience on interimpet in lymphoma were invited to the meeting. Deauville criteria 2010, 2011 october 2012 in menton response criteria. Both hopkins and deauville criteria use 5point scales, however. It is important to note that the nccn modified deauville scores mostly rely on reassessment of initially avid sites and that the nccn recommends fdg pet scans for initial staging and for evaluating residual masses at the end of treatment. The deauville fivepoint scale incorporating the deauville criteria dc is recommended for. The addition of morphological parameters on ct was assessed in relation to therapy response. Conclusion response assessment according to the deauville criteria classification showed good concordance with. Nowadays, 5ds criteria for interpretation of response evaluation with petct have been widely adopted in dlbcl. Deauville, former town in quebec now annexed to the city of cherbrooke. Fdgpet scan in assessing lymphomas and the application of deauville criteria.
Based on the standard of reference, 36 patients 26. Head and neck squamous cell carcinoma hnscc is the sixth leading cancer by incidence worldwide. Deauville archives tdn thoroughbred daily news horse. Fdg petct response assessment criteria for patients with. Furthermore, interim deauville further risk stratified patients compared to baseline ipi p petct in lymphoma tuesday, august 28, 2012 session 5, 11. Read and download ebook honda ntv 650 deauville manual download pdf at public ebook library honda ntv 650 deauville man. The deauville scale and lugano criteria saabry osmany, md, facnm the deauville scale and lugano criteria are used for assessment, staging and response of hodgkin lymphoma hl and nonhodgkin lymphoma nhl.
Prognostic value and clinical impact of 18fdgpet in the. Dlbcl patients with highrisk aaipi 23 have a 5year progressionfree survival pfs of only 40% following rchop. A total of 33 mm patients were enrolled in this retrospective study. Deauville score the deauville criteria uses a five point scale based on visual analysis. Risk stratification on the basis of deauville score on petct. Staging, response assessment and follow up emanuele zucca, md. Deauville is a commune in the calvados departement in the bassenormandie region of france. Qualitative visual trichotomous assessment improves the. Using this method, a deauville score of 1 or 2 is accepted as a complete response to treatment and, especially for interim scans, a score of 3 is also often taken as a complete response. This algorithm has been developed for md anderson using a multidisciplinary approach considering circumstances particular to md andersons specific patient. The results of ipet using the deauville criteria were not predictive of the survival outcomes in patients with mycr lymphoma. The qvta criteria have the same negative criteria as the deauville criteria, but different positive criteria.
If strategies to reduce the development of relapsedrefractory disease in mycr patients will be investigated, we would not advise that they be implemented according to the ipet results. The deauville criteria were used for nodal and extranodal disease. Deauville scores 4 or 5 assessed by fluorine18 fluorodeoxyglucose positron emission tomography. Preautologous transplantation petct using deauville criteria is an. The deauville consensus eliminated the size criterion and introduced the liver as a second reference structure in addition to the mediastinum. According to our findings, we recommend the use of deauville criteria in reporting. These criteria are based on the visual interpretation of the fdguptake which is related to the mediastinum corresponding to the blood pool and the liver. Radiopaedias mission is to create the best radiology reference the world has ever seen and to make it available for free, for ever, for all. Files are available under licenses specified on their description page. Pdf the use of deauville criteria in followup assessment. Deauville fivepoint scale radiology reference article. The use of deauville criteria in followup assessment of.
The deauville score is used throughout the nccn recommendations and an example of a recommendation flow chart is given below. The deauville 5ps is recommended for reporting response. The arqana breeze up sale, which released its catalogue earlier this week, could be rescheduled for either june 3 or 4 depending on the covid19 situation, the sales company announced on saturday. What 18ffdg pet responseassessment method best predicts. The qpet value is the quotient of these measurements. Posttreatment fdg petct in head and neck carcinoma. Many clinicians order a routine, interim petct ipet after 2, 3, or 4 cycles of chemotherapy in diffuse large bcell lymphoma dlbcl patients, although results are conflicting and many lymphoma experts believe that its use in this setting is investigational. The disease staging is established as nodal dlbcl according to the ann. This page was last edited on 10 november 2019, at 17. Preautologous transplantation petct using deauville. Modifying therapy in patients with advanced hodgkins. The deauville 5point scoring system is an internationally accepted and utilized fivepoint. Full text risk stratification of diffuse large bcell.
The variation between the ds plus classification and duriesalmon staging. Feb 24, 2016 positron emission tomography pet response criteria in solid tumors percist 1. Analysis of the deauville criteria for the assessment of interim pet in advanced stage hodgkin lymphoma patients enrolled in the ivs study part i. Furthermore, interim deauville further risk stratified patients compared to baseline ipi p deauville criteria carries prognostic value in ptcl. More recently, in a retrospective analysis of 76 unselected patients with hl, we showed that eight patients with negative interimpet deauville. This international confirmatory study retrospectively evaluated 114 patients with. Fdgpet interpreted by deauville criteria prior to allogeneic. Overall response by deauville criteria showed concordance with ihp. The use of deauville criteria in followup assessment of response to. Highdose salvage chemotherapy followed by haematopoietic stem cell transplantation hct is the standard of care in. It has shown promising results in patients diagnosed with relapsed or refractory hodgkins lymphoma hl at least comparable to allogeneic transplant from siblings or unrelated donors burroughs lm et al. The deauville 5point scoring system is an internationally accepted and utilized fivepoint scoring system for the fluorodeoxyglucose fdg avidity of a hodgkin lymphoma or nonhodgkin lymphoma tumor mass as seen on fdg positron emission tomography. According to the peter mac criteria a partial metabolic response is defined as any appreciable. According to the deauville criteria 9 a five point scoring system is used for the analysis of petct scan at diagnosis and during the course of treatment.
In this cohort, interim pet more accurately identified patients at risk of poor outcome compared to baseline ipi and pit. Using a 5point deauville scale suggests a visual or semiquantitative comparison of. On the road, again find, read and cite all the research you need. Any information contained in this pdf file is automatically generated from digital. The role of interim petct in guiding therapeutic strategies in diffuse large bcell lymphoma dlbcl is debated, mainly because interpretation rules vary among centres. This study aimed to explore the reproducibility and confirm the prognostic value of early petct using the deauville criteria and. All structured data from the file and property namespaces is available under the creative commons cc0 license.
Read and download ebook honda ntv 650 deauville service manual part1 pdf at public ebook library honda ntv 650 deauvill. Pdf fdg pet for therapy monitoring in hodgkin and nonhodgkin. Diagram 1 from nccn guidelines on the role of deauville criteria in restaging stage ia, iia favourable hodgkin lymphoma after chemotherapy. We aimed at comparing the duriesalmon plus ds plus staging system based on italian myeloma criteria for pet use impetus with other two staging systems in predicting prognosis of patients with all stages of newly diagnosed multiple myeloma mm. Dec 08, 2012 many clinicians order a routine, interim petct ipet after 2, 3, or 4 cycles of chemotherapy in diffuse large bcell lymphoma dlbcl patients, although results are conflicting and many lymphoma experts believe that its use in this setting is investigational. Interim petct in the management of diffuse large bcell. Request pdf on aug 30, 2017, michel meignan and others published interim pet in lymphoma. C was reported as stable metabolic disease by eortc and percist but as partial metabolic response by peter mac and deauville. Response assessment according to the deauville criteria classification showed good concordance with ihp classification. Interim petct result is not predictive of survival in. The diagnostic efficiency of the 3 criteria for treatment e were used as the gold standard. Negative predictive value npv of ci and 18 fdgpet were 73 and 93%, 18.
Haploidentical stem cell transplantation haplohsct with. In the deauville criteria, 1 means no abnormal fdg. Petct in lymphoma tuesday, august 28, 2012 session 5, 11. Peter mac and deauville criteria are visual criteria very little peter mac is used in nsclc or none deauville are used. All fdgpet scans were obtained within 4 weeks prior to allohct. Deauville scores and qpetvalues were determined in 898 pediatric hodgkins lymphoma patients after two oepa chemotherapy cycles.
The beauty of the deauville score is that we are our own control. Qualitative visual trichotomous assessment improves the value. Positron emission tomography pet response criteria in solid tumors percist 1. Version 4 121712 use of londondeauville criteria for interim response assessment in hodgkin and aggressive nonhodgkin lymphoma based on visual interpretation of interimpet pet2 this does not require comparison to a baseline pet, but.
1193 1152 570 984 837 337 841 84 431 133 680 540 841 549 1253 60 199 1505 1061 678 1505 1066 1136 587 1593 46 381 1120 513 1368 395 315 1312 1482 592 212 1341 236